Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LP43_1264Hypothetical protein. (250 aa)    
Predicted Functional Partners:
LP43_1263
Hemoglobin-like protein HbO.
       0.774
LP43_0919
Putative hydrolase (metallo-beta-lactamase superfamily).
      
 0.602
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
    
 0.602
LP43_1518
Quinolinate phosphoribosyltransferase [decarboxylating]; Belongs to the NadC/ModD family.
    
 0.565
LP43_1262
Formaldehyde activating enzyme.
       0.561
surE
5-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
  0.486
nadE
NAD synthetase/Glutamine amidotransferase chain of NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.481
LP43_2033
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
    
  0.470
LP43_1340
Nucleoside triphosphate pyrophosphohydrolase MazG.
     
  0.461
LP43_2202
5'-nucleotidase.
     
  0.458
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
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