Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LP43_1329C factor cell-cell signaling protein. (235 aa)    
Predicted Functional Partners:
LP43_0241
Glutamate synthase [NADPH] subunit alpha.
     
 0.915
LP43_1212
Methane monooxygenase component C.
  
 0.798
mgdC
N-methyl glutamate dehydrogenase/oxidoreductase subunit C; Belongs to the GcvT family.
   
 0.717
LP43_0901
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 
 0.700
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 0.686
LP43_0858
Hypothetical protein.
  
 0.675
LP43_1401
Flavodoxin reductase (ferredoxin-NADPH reductases) family 1/Vanillate O-demethylase oxidoreductase.
   
 0.672
LP43_0559
InaA protein.
    
  0.639
LP43_2216
Malonyl CoA-acyl carrier protein transacylase.
  
 0.610
LP43_0281
Hypothetical protein.
    
  0.605
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
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