Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cmoAtRNA (uridine-5-oxyacetic acid methyl ester) 34 synthase; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM). (244 aa)    
Predicted Functional Partners:
cmoB
tRNA (5-methoxyuridine) 34 synthase; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
 
 0.978
LP43_1350
Putative molecular chaperone.
  
    0.776
cmoM
S-adenosylmethionine-dependent methyltransferase; Catalyzes the methylation of 5-carboxymethoxyuridine (cmo5U) to form 5-methoxycarbonylmethoxyuridine (mcmo5U) at position 34 in tRNAs; Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoM family.
 
 
 0.680
LP43_2319
Hypothetical protein.
    
 0.675
LP43_0740
Glutathione S-transfersae-related protein.
  
  
 0.651
mgdC
N-methyl glutamate dehydrogenase/oxidoreductase subunit C; Belongs to the GcvT family.
     
 0.631
LP43_0575
Intracellular septation protein IspA; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family.
   
    0.630
LP43_1351
Hypothetical protein.
       0.552
LP43_1729
Octaprenyl-diphosphate synthase/Dimethylallyltransferase/Geranyltranstransferase (farnesyldiphosphate synthase)/Geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family.
   
  0.546
LP43_0476
Octaprenyl-diphosphate synthase/Dimethylallyltransferase/Geranyltranstransferase (farnesyldiphosphate synthase)/Geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family.
   
  0.545
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
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