Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
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[Homology]
Score
yfjGYfjG. (136 aa)    
Predicted Functional Partners:
yfjF
YfjF; Belongs to the UPF0125 (RnfH) family.
 
  
 0.930
ctaA
Heme A synthase, cytochrome oxidase biogenesis protein Cox15-CtaA.
    
  0.769
ubiB
Ubiquinone biosynthesis monooxygenase UbiB; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
  
 
 
 0.763
LP43_0589
Phosphopantothenoylcysteine decarboxylase/Phosphopantothenoylcysteine synthetase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
     
  0.710
LP43_1448
Sodium-dependent transporter family protein; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
       0.710
smpB
tmRNA-binding protein SmpB; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switc [...]
  
    0.584
bioC
Biotin synthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.
  
     0.541
LP43_0977
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase.
  
     0.517
ctaG
Cytochrome oxidase biogenesis protein Cox11-CtaG.
   
 
  0.499
LP43_0502
1-acyl-sn-glycerol-3-phosphate acyltransferase.
  
     0.483
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
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