Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pilB-2Type IV fimbrial assembly, ATPase PilB. (547 aa)    
Predicted Functional Partners:
pilC-2
Type IV fimbrial assembly protein PilC.
 
 
 0.991
pilC
Type IV fimbrial assembly protein PilC.
 
 
 0.974
LP43_1505
Hypothetical protein.
 
 0.940
LP43_1504
Hypothetical protein.
  
 0.936
LP43_0536
Leader peptidase (Prepilin peptidase)/N-methyltransferase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
 
 0.884
LP43_1506
Hypothetical protein.
 
 0.870
pilN
Type IV pilus biogenesis protein PilN.
   
 
 0.791
LP43_2224
Type IV pilus biogenesis protein PilZ.
    
 
 0.787
LP43_1502
Hypothetical protein.
       0.773
LP43_1503
Hypothetical protein.
       0.773
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
Server load: low (12%) [HD]