Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LP43_1587Sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (472 aa)    
Predicted Functional Partners:
LP43_1586
Sodium:alanine symporter.
 
     0.844
LP43_2118
Hypothetical protein.
   
 
 0.784
LP43_1589
Aspartokinase associated with ectoine biosynthesis.
 
   
 0.763
LP43_1588
TPR repeat containing protein.
 
     0.748
LP43_2228
Hypothetical protein.
     
 0.711
LP43_2231
Hypothetical protein.
     
 0.711
LP43_0216
Proline/sodium symporter PutP; (TC 2.A.21.2.1); Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
     0.688
ectC
L-ectoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant.
 
     0.601
LP43_2119
Hypothetical protein.
     
 0.587
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
    0.570
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
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