Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ectAL-2,4-diaminobutyric acid acetyltransferase; Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A. (169 aa)    
Predicted Functional Partners:
ectC
L-ectoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant.
 
  
  0.991
LP43_1591
Diaminobutyrate-pyruvate aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.991
LP43_2092
Diaminobutyrate-pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.986
LP43_1589
Aspartokinase associated with ectoine biosynthesis.
 
   
 0.865
LP43_2013
Chorismate mutase I/Prephenate dehydratase.
    
  0.852
LP43_0241
Glutamate synthase [NADPH] subunit alpha.
   
 
 0.790
LP43_0058
Siderophore biosynthesis L-2,4-diaminobutyrate decarboxylase.
    
 0.734
LP43_1594
Putative regulatory protein associated with the ectoine operon.
 
     0.732
LP43_0375
Pyruvate carboxyl transferase subunit B.
     
  0.684
LP43_2064
Oxaloacetate decarboxylase alpha chain.
     
  0.684
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
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