Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lapAHypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. (97 aa)    
Predicted Functional Partners:
lapB
Heat shock protein YciM, precursor; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.
 
   
 0.921
LP43_1673
Hypothetical protein.
 
     0.822
LP43_1671
Arsenate reductase.
       0.774
LP43_1672
Trp repressor-binding protein; Belongs to the WrbA family.
       0.773
LP43_1674
Hypothetical protein.
       0.625
LP43_1880
LppC putative lipoprotein.
  
     0.603
LP43_1668
4Fe-4S ferredoxin, iron-sulfur binding; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
 
     0.592
lolB
Outer membrane lipoprotein LolB precursor; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.
  
     0.488
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
  
     0.470
LP43_0655
Protein YigP.
  
     0.469
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
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