STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LP43_1884Hypothetical protein; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein. (123 aa)    
Predicted Functional Partners:
LP43_0585
Chemotaxis protein methyltransferase CheR; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
  
 
   0.914
LP43_0939
CheW domain protein.
  
     0.745
LP43_1593
Positive regulator of CheA protein activity (CheW).
  
     0.653
LP43_0888
Hypothetical protein.
  
   
 0.619
LP43_0293
Pentapeptide repeat domain protein.
  
    0.597
fliL-2
Flagellar biosynthesis protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
  
     0.561
flaG
Flagellin protein FlaG.
  
     0.557
LP43_1883
Protoporphyrinogen IX oxidase HemJ.
       0.557
LP43_0372
Hypothetical protein.
  
    0.531
LP43_1091
Hypothetical protein.
  
     0.528
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
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