Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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co-expression
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gene co-occurrence
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LP43_1966Succinate dehydrogenase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (242 aa)    
Predicted Functional Partners:
LP43_1964
Succinate dehydrogenase cytochrome b subunit.
 
 0.999
LP43_1965
Succinate dehydrogenase flavoprotein subunit.
 
 0.999
LP43_0842
Tungsten-containing formate dehydrogenase beta subunit.
   
 
 0.997
LP43_2532
Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.997
LP43_2026
Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex.
  
 0.995
sucD
Succinyl-CoA ligase [ADP-forming] alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 0.990
sucC
Succinyl-CoA ligase [ADP-forming] beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 0.986
LP43_0524
Ubiquinol--cytochrome C reductase iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
  
 0.983
LP43_0522
Ubiquinol--cytochrome C oxidoreductase, cytochrome C1 subunit.
   
 
 0.963
LP43_1002
NADH-ubiquinone oxidoreductase chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.
   
 
 0.963
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
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