Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LP43_1978Isopropylmalate/homocitrate/citramalate synthase. (135 aa)    
Predicted Functional Partners:
LP43_1979
Putative acetyltransferase.
 
     0.955
LP43_1980
Hydrolase, carbon-nitrogen family.
 
     0.942
LP43_1975
Putative Carboxynorspermidine dehydrogenase.
       0.530
LP43_1976
Putative Carboxynorspermidine decarboxylase; Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine; Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.
       0.498
LP43_1977
Agmatinase; Belongs to the arginase family.
       0.498
LP43_1981
Scaffold protein for [4Fe-4S] cluster assembly ApbC, MRP-like; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
       0.497
LP43_0058
Siderophore biosynthesis L-2,4-diaminobutyrate decarboxylase.
     
  0.461
bioA
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
     
  0.461
LP43_1702
Gamma-glutamyltranspeptidase.
     
  0.461
LP43_1965
Succinate dehydrogenase flavoprotein subunit.
     
  0.461
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
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