Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LP43_2074Lead, cadmium, zinc and mercury transporting ATPase/Copper-translocating P-type ATPase. (734 aa)    
Predicted Functional Partners:
merP
Periplasmic mercury(+2) binding protein; Involved in mercury resistance. Acts as a mercury scavenger that specifically binds to a mercuric ion in the periplasm and probably passes it to the cytoplasmic mercuric reductase MerA via the mercuric transport protein MerT.
 
 
 0.895
LP43_1212
Methane monooxygenase component C.
    
 0.864
LP43_0116
Hypothetical protein.
  
 
 0.836
LP43_0858
Hypothetical protein.
    
 0.823
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
 0.808
ribB-2
3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
 0.808
LP43_1401
Flavodoxin reductase (ferredoxin-NADPH reductases) family 1/Vanillate O-demethylase oxidoreductase.
    
 0.788
LP43_1994
Diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s).
    
  0.659
LP43_0109
Multicopper oxidase.
 
  
 0.652
LP43_0103
Cobalt/zinc/cadmium efflux RND transporter, membrane fusion protein, CzcB family; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
    
 0.551
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
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