LP43_2135 protein (Methylophaga thiooxydans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

LP43_2135

Dienelactone hydrolase. (247 aa)

Predicted Functional Partners:

LP43_2134

0.556

nadK

0.444

ndk

0.429

LP43_1212

0.415

LP43_0281

0.412

LP43_0780

0.412

Your Current Organism:

Methylophaga thiooxydans

NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LP43_0281	LP43_1212	LP43_0281	LP43_1212	Hypothetical protein.	Methane monooxygenase component C.	0.433
LP43_0281	LP43_2135	LP43_0281	LP43_2135	Hypothetical protein.	Dienelactone hydrolase.	0.412
LP43_0281	ndk	LP43_0281	LP43_2270	Hypothetical protein.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.819
LP43_0780	LP43_2135	LP43_0780	LP43_2135	Hypothetical protein.	Dienelactone hydrolase.	0.412
LP43_0780	ndk	LP43_0780	LP43_2270	Hypothetical protein.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.798
LP43_1212	LP43_0281	LP43_1212	LP43_0281	Methane monooxygenase component C.	Hypothetical protein.	0.433
LP43_1212	LP43_2135	LP43_1212	LP43_2135	Methane monooxygenase component C.	Dienelactone hydrolase.	0.415
LP43_1212	ndk	LP43_1212	LP43_2270	Methane monooxygenase component C.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.412
LP43_2134	LP43_2135	LP43_2134	LP43_2135	Hypothetical protein.	Dienelactone hydrolase.	0.556
LP43_2135	LP43_0281	LP43_2135	LP43_0281	Dienelactone hydrolase.	Hypothetical protein.	0.412
LP43_2135	LP43_0780	LP43_2135	LP43_0780	Dienelactone hydrolase.	Hypothetical protein.	0.412
LP43_2135	LP43_1212	LP43_2135	LP43_1212	Dienelactone hydrolase.	Methane monooxygenase component C.	0.415
LP43_2135	LP43_2134	LP43_2135	LP43_2134	Dienelactone hydrolase.	Hypothetical protein.	0.556
LP43_2135	nadK	LP43_2135	LP43_2271	Dienelactone hydrolase.	NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	0.444
LP43_2135	ndk	LP43_2135	LP43_2270	Dienelactone hydrolase.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.429
nadK	LP43_2135	LP43_2271	LP43_2135	NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	Dienelactone hydrolase.	0.444
nadK	ndk	LP43_2271	LP43_2270	NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.492
ndk	LP43_0281	LP43_2270	LP43_0281	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Hypothetical protein.	0.819
ndk	LP43_0780	LP43_2270	LP43_0780	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Hypothetical protein.	0.798
ndk	LP43_1212	LP43_2270	LP43_1212	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Methane monooxygenase component C.	0.412

page 1 of 2

Server load: low (12%) [HD]

Permalink

Network

Neighborhood

Experiments

Co-occurrence

Databases

Co-expression

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About