Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LP43_2136Isocitrate dehydrogenase [NADP]/Monomeric isocitrate dehydrogenase [NADP]; Belongs to the monomeric-type IDH family. (739 aa)    
Predicted Functional Partners:
LP43_0241
Glutamate synthase [NADPH] subunit alpha.
     
 0.952
LP43_1668
4Fe-4S ferredoxin, iron-sulfur binding; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
  
 
 0.941
LP43_2034
Aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family.
  
 
 0.940
LP43_2033
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
   
  0.856
LP43_0196
NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.814
argH
Argininosuccinate lyase.
     
 0.793
LP43_0240
Glutamate synthase [NADPH] subunit beta.
     
  0.793
LP43_2094
Succinate-semialdehyde dehydrogenase [NAD]/Succinate-semialdehyde dehydrogenase [NADP+].
     
  0.793
LP43_2355
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
    
  0.793
LP43_2026
Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex.
     
 0.752
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
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