STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LP43_2158SAM-dependent methyltransferase SCO3452. (346 aa)    
Predicted Functional Partners:
LP43_2159
Radical SAM domain protein.
     0.943
LP43_2163
Hypothetical protein.
 
     0.861
LP43_2162
Glycosyl transferase, family 2.
 
    0.847
LP43_2161
Hypothetical protein.
 
     0.670
LP43_2160
FAD-dependent NAD(P)-disulfide oxidoreductase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
 
  
  0.668
LP43_2319
Hypothetical protein.
  
 
 0.646
mgdC
N-methyl glutamate dehydrogenase/oxidoreductase subunit C; Belongs to the GcvT family.
     
 0.605
LP43_0901
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
 
  
 0.597
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
 
 0.579
LP43_2157
Type I iodothyronine deiodinase.
 
     0.554
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
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