Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LP43_2299Response regulator NasT. (209 aa)    
Predicted Functional Partners:
LP43_2298
Nitrate ABC transporter, nitrate-binding protein.
 
  
 0.920
LP43_2305
Nitrite reductase [NAD(P)H] large subunit; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.870
LP43_2303
Assimilatory nitrate reductase large subunit NapA; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
 
  
 0.868
LP43_0647
Hypothetical protein.
  
 
 0.808
LP43_2304
Nitrite reductase [NAD(P)H] small subunit.
 
  
 0.799
LP43_2300
Membrane-associated methyl-accepting chemotaxis protein with HAMP domain.
       0.773
LP43_2297
Nitrate ABC transporter, permease protein.
 
   
 0.765
cysG
Uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
  
 
 0.660
LP43_2301
Hypothetical protein.
       0.658
LP43_2296
Nitrate ABC transporter, ATP-binding protein.
 
   
 0.644
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
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