Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LP43_2302Hypothetical protein. (418 aa)    
Predicted Functional Partners:
LP43_1765
Outer membrane chaperone Skp (OmpH) precursor / Outer membrane protein H precursor; Belongs to the skp family.
    
 
 0.797
secA
Protein export cytoplasm protein SecA ATPase RNA helicase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.
    
 
 0.720
LP43_1917
TonB-dependent receptor.
  
   
 0.660
bamA
Outer membrane protein assembly factor YaeT precursor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
    
 
 0.640
LP43_1268
Hypothetical protein.
  
     0.636
bamD
Lipoprotein assembly complex component; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
   
 
 0.617
LP43_0194
HtrA protease/chaperone protein/Serine protease (Protease DO); Belongs to the peptidase S1C family.
    
 
 0.613
LP43_2350
Serine protease precursor MucD/AlgY associated with sigma factor RpoE; Belongs to the peptidase S1C family.
    
 
 0.613
LP43_2378
Hypothetical protein.
  
     0.613
LP43_2181
Outer membrane protein NlpB.
    
 
 0.611
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
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