Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LP43_2341Hypothetical protein. (325 aa)    
Predicted Functional Partners:
LP43_0842
Tungsten-containing formate dehydrogenase beta subunit.
   
 0.993
LP43_2339
Long-chain-fatty-acid--CoA ligase.
  
 0.985
LP43_2216
Malonyl CoA-acyl carrier protein transacylase.
  
 0.952
LP43_2337
Anthrachelin biosynthesis protein AsbA/Siderophore synthetase superfamily, group A/Siderophore synthetase large component, acetyltransferase.
  
 
  0.929
LP43_2338
Anthrachelin biosynthesis protein AsbB/Siderophore synthetase superfamily, group C/Siderophore synthetase component, ligase.
  
 
  0.929
rplU
LSU ribosomal protein L21p; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
   
 0.927
nuoC
NADH-ubiquinone oxidoreductase chain C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family.
   
 0.923
rplQ
LSU ribosomal protein L17p.
   
  0.913
rplM
LSU ribosomal protein L13p (L13Ae); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
  0.912
LP43_1475
Enoyl-[acyl-carrier-protein] reductase [NADH].
  
 0.911
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
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