| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LP43_0901 | LP43_1695 | LP43_0901 | LP43_1695 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Vitamin B12 ABC transporter, B12-binding component BtuF. | 0.466 |
| LP43_0901 | LP43_2346 | LP43_0901 | LP43_2346 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Putative periplasmic substrate-binding transport protein. | 0.466 |
| LP43_0901 | cysG | LP43_0901 | LP43_1521 | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.784 |
| LP43_1695 | LP43_0901 | LP43_1695 | LP43_0901 | Vitamin B12 ABC transporter, B12-binding component BtuF. | 5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.466 |
| LP43_1695 | LP43_1696 | LP43_1695 | LP43_1696 | Vitamin B12 ABC transporter, B12-binding component BtuF. | Iron(III) ABC transporter, ATP-binding protein. | 0.993 |
| LP43_1695 | LP43_1697 | LP43_1695 | LP43_1697 | Vitamin B12 ABC transporter, B12-binding component BtuF. | Hypothetical protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.993 |
| LP43_1695 | LP43_2344 | LP43_1695 | LP43_2344 | Vitamin B12 ABC transporter, B12-binding component BtuF. | Ferrichrome transport ATP-binding protein FhuC; (TC 3.A.1.14.3). | 0.962 |
| LP43_1695 | LP43_2345 | LP43_1695 | LP43_2345 | Vitamin B12 ABC transporter, B12-binding component BtuF. | Iron(III) dicitrate transport system permease protein FecD; (TC 3.A.1.14.1); Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.969 |
| LP43_1695 | LP43_2346 | LP43_1695 | LP43_2346 | Vitamin B12 ABC transporter, B12-binding component BtuF. | Putative periplasmic substrate-binding transport protein. | 0.472 |
| LP43_1695 | cysG | LP43_1695 | LP43_1521 | Vitamin B12 ABC transporter, B12-binding component BtuF. | Uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.477 |
| LP43_1696 | LP43_1695 | LP43_1696 | LP43_1695 | Iron(III) ABC transporter, ATP-binding protein. | Vitamin B12 ABC transporter, B12-binding component BtuF. | 0.993 |
| LP43_1696 | LP43_1697 | LP43_1696 | LP43_1697 | Iron(III) ABC transporter, ATP-binding protein. | Hypothetical protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.996 |
| LP43_1696 | LP43_2345 | LP43_1696 | LP43_2345 | Iron(III) ABC transporter, ATP-binding protein. | Iron(III) dicitrate transport system permease protein FecD; (TC 3.A.1.14.1); Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.985 |
| LP43_1696 | LP43_2346 | LP43_1696 | LP43_2346 | Iron(III) ABC transporter, ATP-binding protein. | Putative periplasmic substrate-binding transport protein. | 0.908 |
| LP43_1697 | LP43_1695 | LP43_1697 | LP43_1695 | Hypothetical protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | Vitamin B12 ABC transporter, B12-binding component BtuF. | 0.993 |
| LP43_1697 | LP43_1696 | LP43_1697 | LP43_1696 | Hypothetical protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | Iron(III) ABC transporter, ATP-binding protein. | 0.996 |
| LP43_1697 | LP43_2344 | LP43_1697 | LP43_2344 | Hypothetical protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | Ferrichrome transport ATP-binding protein FhuC; (TC 3.A.1.14.3). | 0.984 |
| LP43_1697 | LP43_2346 | LP43_1697 | LP43_2346 | Hypothetical protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | Putative periplasmic substrate-binding transport protein. | 0.908 |
| LP43_2343 | LP43_2344 | LP43_2343 | LP43_2344 | Hypothetical protein. | Ferrichrome transport ATP-binding protein FhuC; (TC 3.A.1.14.3). | 0.858 |
| LP43_2343 | LP43_2345 | LP43_2343 | LP43_2345 | Hypothetical protein. | Iron(III) dicitrate transport system permease protein FecD; (TC 3.A.1.14.1); Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.826 |