Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LP43_2373Type cbb3 cytochrome oxidase biogenesis protein CcoS, involved in heme b insertion. (68 aa)    
Predicted Functional Partners:
ccoO
Cytochrome c oxidase subunit CcoO.
 
 
 0.853
ccoP
Cytochrome c oxidase subunit CcoP; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
 
 
 0.843
LP43_2375
Hypothetical protein.
 
  
 0.811
LP43_1246
Type cbb3 cytochrome oxidase biogenesis protein CcoG, involved in Cu oxidation.
 
  
 0.810
LP43_2374
FUPA27 P-type ATPase.
 
  
 0.796
LP43_1870
Cytochrome c oxidase polypeptide II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
    
 0.717
LP43_1187
Cytochrome c oxidase subunit CcoN.
 
  
 0.697
ccoN
Cytochrome c oxidase subunit CcoN; Belongs to the heme-copper respiratory oxidase family.
 
  
 0.697
LP43_1249
Cytochrome c oxidase subunit CcoN; Belongs to the heme-copper respiratory oxidase family.
 
  
 0.694
LP43_2372
Diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s).
       0.610
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
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