Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LP43_2473ABC-type multidrug transport system, permease component. (260 aa)    
Predicted Functional Partners:
LP43_2472
ABC-type multidrug transport system, ATPase component.
 
 0.981
LP43_0805
ABC transporter, ATP-binding protein.
 
 0.655
LP43_0266
Hypothetical protein.
  
  
 0.601
LP43_1297
Nitroreductase.
  
    0.556
LP43_2030
Oxygen-insensitive NAD(P)H nitroreductase/Dihydropteridine reductase.
  
    0.556
LP43_2387
Oxygen-insensitive NADPH nitroreductase.
  
    0.556
LP43_2510
Cobalamin biosynthesis protein BluB/5,6-dimethylbenzimidazole synthase, flavin destructase family.
  
    0.556
mutH
DNA mismatch repair endonuclease MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair. Belongs to the MutH family.
       0.553
LP43_0806
Efflux ABC transporter, permease protein.
  
  
 
0.519
LP43_0749
ABC transporter, ATP-binding protein.
  
 
 0.488
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
Server load: low (14%) [HD]