Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LP43_2483PTS IIA-like nitrogen-regulatory protein PtsN. (153 aa)    
Predicted Functional Partners:
LP43_2486
Phosphocarrier protein, nitrogen regulation associated.
 
 
 0.988
LP43_2482
Ribosome hibernation protein YhbH.
 
  
 0.974
LP43_2487
Phosphoenolpyruvate-protein phosphotransferase of PTS system; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 
 0.960
LP43_2485
PTS system fructose subfamily IIA component.
 
 
 0.936
LP43_2484
HPr kinase/phosphorylase.
 
   
 0.932
LP43_2481
RNA polymerase sigma-54 factor RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.879
LP43_0401
Multiple polyol-specific dehydrogenase; Belongs to the mannitol dehydrogenase family.
  
 
 0.837
LP43_0463
Fructose-bisphosphate aldolase class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
  
 
 0.753
LP43_1387
Fructokinase.
    
 0.710
LP43_2488
Magnesium transporter; Acts as a magnesium transporter.
 
   
 0.600
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
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