Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LP43_2526DNA-damage-inducible protein F. (420 aa)    
Predicted Functional Partners:
rplO
LSU ribosomal protein L15p (L27Ae); Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
    
   0.625
LP43_0460
NAD-dependent glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
   
  
 0.609
LP43_1604
SSU ribosomal protein S1p; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
   
    0.575
LP43_0474
Phytoene synthase.
   
    0.559
LP43_1927
Phytoene synthase.
   
    0.559
hppA
Pyrophosphate-energized proton pump; Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane. Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
       0.505
rplW
LSU ribosomal protein L23p (L23Ae); One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.
    
   0.504
rpsQ
SSU ribosomal protein S17p (S11e); One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
    
   0.504
rplX
LSU ribosomal protein L24p (L26e); One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
    
   0.504
rplD
LSU ribosomal protein L4p (L1e); Forms part of the polypeptide exit tunnel.
    
   0.431
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
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