Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
msrAPeptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (177 aa)    
Predicted Functional Partners:
msrB
TIGRFAM: methionine-R-sulfoxide reductase; PFAM: Methionine sulfoxide reductase B; Belongs to the MsrB Met sulfoxide reductase family.
 
 0.990
Swit_2900
TIGRFAM: methionine-R-sulfoxide reductase; PFAM: Methionine sulfoxide reductase B.
 
 0.987
Swit_0542
PFAM: cytochrome c biogenesis protein, transmembrane region.
   
 
 0.723
Swit_3733
Redoxin domain protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein.
   
 0.639
Swit_2865
Redoxin domain protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein.
   
 0.573
Swit_3991
TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein.
   
 0.573
Swit_4364
TIGRFAM: methylamine dehydrogenase accessory protein MauD; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein.
   
 0.573
Swit_0558
Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
  
 
 0.545
Swit_1124
PFAM: glutaredoxin.
  
 
 0.545
Swit_4793
PFAM: protein of unknown function DUF470; protein of unknown function DUF471; protein of unknown function DUF472.
     
 0.494
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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