Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_0175Transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR; Autoinducer-binding domain protein. (254 aa)    
Predicted Functional Partners:
Swit_2540
PFAM: response regulator receiver.
  
 
 0.634
Swit_0176
RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma-70; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; Belongs to the sigma-70 factor family. ECF subfamily.
  
  
 0.628
Swit_1477
Putative adenylate/guanylate cyclase; TIGRFAM: PAS sensor protein; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; GAF domain protein; histidine kinase, HAMP region domain protein; PAS fold-4 domain protein; PAS fold domain protein.
  
 
 0.586
Swit_0803
Putative signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein.
  
 
 0.583
Swit_0174
Hypothetical protein.
       0.539
Swit_4492
PFAM: polysaccharide deacetylase.
  
  
 0.534
Swit_1111
Hypothetical protein.
 
     0.510
Swit_4560
Hypothetical protein.
 
   
 0.509
Swit_4359
PFAM: regulatory protein, LuxR.
 
 
0.503
Swit_3662
Hypothetical protein.
 
     0.498
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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