Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_0205PFAM: Cupin 2, conserved barrel domain protein. (110 aa)    
Predicted Functional Partners:
Swit_0206
Secreted Zn-dependent protease-like protein.
       0.781
cobB
PFAM: Silent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily.
       0.781
Swit_2371
PFAM: sugar transferase.
  
  
 0.708
Swit_1765
PFAM: amidohydrolase 2.
 
     0.574
Swit_4009
PFAM: glycosyl transferase, group 1; TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein.
  
  
 0.568
nth
Endonuclease III / DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
       0.553
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
       0.547
Swit_4557
Transcriptional regulator, AraC family; PFAM: Cupin 2, conserved barrel domain protein; SMART: helix-turn-helix- domain containing protein, AraC type.
 
 
 0.467
Swit_0326
Transcriptional regulator, AraC family with amidase-like domain; PFAM: helix-turn-helix- domain containing protein, AraC type.
 
 
 
 0.416
Swit_2640
PFAM: sugar transferase.
  
  
 0.407
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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