Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_0259PFAM: periplasmic binding protein. (290 aa)    
Predicted Functional Partners:
Swit_0257
PFAM: ABC transporter related; SMART: AAA ATPase.
 
 
 0.990
Swit_0258
PFAM: transport system permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.988
Swit_3189
PFAM: TonB-dependent receptor; TonB-dependent receptor, plug.
 
  
 0.729
Swit_0590
PFAM: cyclic nucleotide-binding; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin, iron-sulfur binding domain protein.
  
  
 0.540
Swit_1191
PFAM: TonB-dependent receptor; TonB-dependent receptor, plug.
 
  
 0.469
Swit_2038
PFAM: isochorismatase hydrolase.
  
  
 0.455
Swit_3748
TIGRFAM: TonB family protein.
 
  
 0.437
Swit_2891
TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein.
  
  
 0.407
cobQ
Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
  
 0.402
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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