Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_0295PFAM: short-chain dehydrogenase/reductase SDR; KR; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (320 aa)    
Predicted Functional Partners:
Swit_3404
3-alpha,7-alpha, 12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoAhydratase; PFAM: MaoC domain protein dehydratase.
 0.967
Swit_4599
TIGRFAM: acetoacetyl-CoA reductase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR.
 
    
0.847
Swit_0296
Palmitoyl-CoA hydrolase; PFAM: acyl-CoA thioesterase.
    
 0.842
Swit_0335
PFAM: short-chain dehydrogenase/reductase SDR; KR.
 
    
0.741
Swit_0297
PFAM: Taurine catabolism dioxygenase TauD/TfdA.
     
 0.720
Swit_0352
PFAM: short-chain dehydrogenase/reductase SDR.
  
     0.648
Swit_4228
PFAM: short-chain dehydrogenase/reductase SDR.
  
     0.626
Swit_2106
PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR.
  
     0.610
Swit_0304
PFAM: short-chain dehydrogenase/reductase SDR; KR.
 
     0.609
Swit_0897
PFAM: short-chain dehydrogenase/reductase SDR.
  
     0.590
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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