Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_0320PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding. (322 aa)    
Predicted Functional Partners:
Swit_0321
1,4-Dihydroxy-2-naphthoate synthase; PFAM: Enoyl-CoA hydratase/isomerase.
  
 0.874
Swit_0322
PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; Belongs to the enoyl-CoA hydratase/isomerase family.
 
0.821
Swit_0323
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain.
 
 0.804
Swit_3602
TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal domain protein; Belongs to the thiolase-like superfamily. Thiolase family.
 
 0.720
Swit_2893
TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
 
 0.718
Swit_0632
TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
 
 0.716
Swit_3795
TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
 
 0.714
Swit_0345
TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
 
 0.711
Swit_1529
PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
 
 0.711
Swit_0342
Propanoyl-CoA C-acyltransferase.
  
 0.672
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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