Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_0347PFAM: Transketolase, central region; Transketolase domain protein. (334 aa)    
Predicted Functional Partners:
Swit_0346
Pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase, E1 component.
 0.994
Swit_1057
Pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase, E1 component.
 0.985
Swit_2270
Pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase, E1 component.
 0.985
Swit_0839
Pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase, E1 component.
 0.980
Swit_1040
PFAM: dehydrogenase, E1 component.
 0.977
Swit_0668
PFAM: dehydrogenase, E1 component.
 0.971
pdhA
Pyruvate dehydrogenase (acetyl-transferring); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.971
Swit_0782
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); PFAM: dehydrogenase, E1 component.
 0.958
Swit_2145
PFAM: dehydrogenase, E1 component.
 0.942
Swit_0348
PFAM: biotin/lipoyl attachment domain-containing protein.
  
 0.895
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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