Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_0394PFAM: regulatory protein, LuxR; Bacterio-opsin activator, HTH domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2. (185 aa)    
Predicted Functional Partners:
Swit_0393
Hypothetical protein.
       0.615
Swit_3861
PFAM: TonB-dependent receptor, plug.
  
     0.542
greB
Transcription elongation factor GreB; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.
       0.520
Swit_0392
Hypothetical protein.
       0.513
Swit_2738
PFAM: CHAP domain containing protein.
 
     0.465
Swit_2153
Hypothetical protein.
  
     0.457
Swit_2814
Transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR.
 
 
 0.421
Swit_3882
Conserved hypothetical protein.
  
     0.414
Swit_4782
PFAM: PDZ/DHR/GLGF domain protein; peptidase M61 domain protein.
  
     0.411
Swit_2844
Hypothetical protein.
  
     0.408
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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