STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swit_0397TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein. (90 aa)    
Predicted Functional Partners:
Swit_0398
PFAM: PTS system fructose subfamily IIA component.
 
 0.997
Swit_0400
Hpr(Ser) kinase/phosphatase.
 
 
 
 0.967
Swit_4505
PTSINtr with GAF domain, PtsP; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing enzyme; GAF domain protein; PEP-utilising enzyme, mobile region; PEP-utilising enzyme domain protein; Belongs to the PEP-utilizing enzyme family.
  
 
 
 0.949
Swit_0399
Uncharacterised P-loop ATPase protein UPF0042; Displays ATPase and GTPase activities.
  
  
 0.900
Swit_2826
PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2.
 
  
 0.866
Swit_1637
Transcriptional regulator, LacI family; PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator.
 
 
 
 0.845
Swit_0402
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein.
  
  
 0.842
Swit_4142
Transcriptional regulator, LacI family; PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator.
 
 
 
 0.839
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
  
  
 0.773
rpsG
SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
  
  
 0.762
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.