STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swit_0401Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein. (529 aa)    
Predicted Functional Partners:
Swit_0402
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein.
 
 0.996
Swit_1160
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; CHASE3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
 
0.928
Swit_2781
PFAM: response regulator receiver.
 
 
 0.845
Swit_2235
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein.
 
 
 0.823
Swit_3577
Two component transcriptional regulator, winged helix family; TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein.
 
 0.823
Swit_2954
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein.
 
 0.813
Swit_0400
Hpr(Ser) kinase/phosphatase.
     
 0.794
Swit_0399
Uncharacterised P-loop ATPase protein UPF0042; Displays ATPase and GTPase activities.
       0.786
Swit_2147
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein.
 
 
 0.781
Swit_3444
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein.
 
 0.780
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.