Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pepALeucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (489 aa)    
Predicted Functional Partners:
gshB
TIGRFAM: glutathione synthetase; PFAM: glutathione synthetase domain protein; glutathione synthetase, ATP-binding; RimK domain protein ATP-grasp; Belongs to the prokaryotic GSH synthase family.
  
 
 0.945
Swit_2754
TIGRFAM: aminopeptidase N; PFAM: Peptidase M1, membrane alanine aminopeptidase-like.
 
 0.939
Swit_0098
PFAM: peptidase M17, leucyl aminopeptidase domain protein; Belongs to the peptidase M17 family.
 
  
 
0.925
Swit_4426
Gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase.
 
 
 0.925
Swit_2655
TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase.
 
 
 0.921
Swit_2364
Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
    
  0.900
Swit_3551
PFAM: aminotransferase, class I and II.
   
 0.839
Swit_4172
PFAM: aminotransferase, class I and II.
   
 0.839
Swit_1210
TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; Belongs to the cysteine synthase/cystathionine beta- synthase family.
   
  0.835
Swit_3958
PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit.
   
  0.835
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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