Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_0558Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. (88 aa)    
Predicted Functional Partners:
secB
Protein translocase subunit secB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.
  
  
 0.918
Swit_0557
PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase.
   
 
 0.883
Swit_1504
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 0.878
Swit_0556
PFAM: protein of unknown function DUF1178.
       0.870
Swit_4712
TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily.
 
 
 0.850
Swit_0559
PFAM: phosphoribosyltransferase.
       0.801
Swit_0560
PFAM: Methyltransferase type 11; Methyltransferase type 12.
  
  
 0.732
Swit_3723
PFAM: Rhodanese domain protein.
  
  
 0.648
Swit_4711
PFAM: BolA family protein; Belongs to the BolA/IbaG family.
 
 
 0.646
gshB
TIGRFAM: glutathione synthetase; PFAM: glutathione synthetase domain protein; glutathione synthetase, ATP-binding; RimK domain protein ATP-grasp; Belongs to the prokaryotic GSH synthase family.
 
   
 0.634
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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