Swit_0612 protein (Sphingomonas wittichii) - STRING interaction network

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Score

Swit_0612

PFAM: YceI family protein; Belongs to the UPF0312 family. (205 aa)

Predicted Functional Partners:

ilvC

0.735

Swit_0583

0.679

Swit_3478

0.659

Swit_0610

0.644

Swit_0613

0.599

Swit_0609

0.495

Your Current Organism:

Sphingomonas wittichii

NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Swit_0583	Swit_0612	Swit_0583	Swit_0612	PFAM: cytochrome B561.	PFAM: YceI family protein; Belongs to the UPF0312 family.	0.679
Swit_0609	Swit_0610	Swit_0609	Swit_0610	TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein.	TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein.	0.999
Swit_0609	Swit_0612	Swit_0609	Swit_0612	TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein.	PFAM: YceI family protein; Belongs to the UPF0312 family.	0.495
Swit_0609	ilvC	Swit_0609	Swit_0611	TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein.	Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.	0.996
Swit_0610	Swit_0609	Swit_0610	Swit_0609	TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein.	TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein.	0.999
Swit_0610	Swit_0612	Swit_0610	Swit_0612	TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein.	PFAM: YceI family protein; Belongs to the UPF0312 family.	0.644
Swit_0610	ilvC	Swit_0610	Swit_0611	TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein.	Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.	0.999
Swit_0612	Swit_0583	Swit_0612	Swit_0583	PFAM: YceI family protein; Belongs to the UPF0312 family.	PFAM: cytochrome B561.	0.679
Swit_0612	Swit_0609	Swit_0612	Swit_0609	PFAM: YceI family protein; Belongs to the UPF0312 family.	TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein.	0.495
Swit_0612	Swit_0610	Swit_0612	Swit_0610	PFAM: YceI family protein; Belongs to the UPF0312 family.	TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein.	0.644
Swit_0612	Swit_0613	Swit_0612	Swit_0613	PFAM: YceI family protein; Belongs to the UPF0312 family.	Hypothetical protein.	0.599
Swit_0612	Swit_3478	Swit_0612	Swit_3478	PFAM: YceI family protein; Belongs to the UPF0312 family.	PFAM: cytochrome B561.	0.659
Swit_0612	ilvC	Swit_0612	Swit_0611	PFAM: YceI family protein; Belongs to the UPF0312 family.	Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.	0.735
Swit_0613	Swit_0612	Swit_0613	Swit_0612	Hypothetical protein.	PFAM: YceI family protein; Belongs to the UPF0312 family.	0.599
Swit_0613	ilvC	Swit_0613	Swit_0611	Hypothetical protein.	Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.	0.424
Swit_3478	Swit_0612	Swit_3478	Swit_0612	PFAM: cytochrome B561.	PFAM: YceI family protein; Belongs to the UPF0312 family.	0.659
ilvC	Swit_0609	Swit_0611	Swit_0609	Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.	TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein.	0.996
ilvC	Swit_0610	Swit_0611	Swit_0610	Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.	TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT domain protein.	0.999
ilvC	Swit_0612	Swit_0611	Swit_0612	Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.	PFAM: YceI family protein; Belongs to the UPF0312 family.	0.735
ilvC	Swit_0613	Swit_0611	Swit_0613	Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.	Hypothetical protein.	0.424

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