Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
Swit_0626PFAM: Activator of Hsp90 ATPase 1 family protein. (152 aa)    
Predicted Functional Partners:
Swit_0625
Transcriptional regulator, ArsR family; PFAM: regulatory protein, ArsR; Helix-turn-helix, type 11 domain protein.
 
  
 0.955
Swit_0627
Peptidase M10, serralysin-like protein; PFAM: Hemolysin-type calcium-binding region; peptidase M12A, astacin; peptidase M10A and M12B, matrixin and adamalysin; Peptidase M10, serralysin-like; SMART: peptidase, metallopeptidase.
  
    0.569
Swit_2435
PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase.
 
     0.556
Swit_1320
PFAM: DGPFAETKE family protein.
 
     0.473
Swit_2571
PFAM: bifunctional deaminase-reductase domain protein.
 
     0.402
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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