Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Swit_0627Peptidase M10, serralysin-like protein; PFAM: Hemolysin-type calcium-binding region; peptidase M12A, astacin; peptidase M10A and M12B, matrixin and adamalysin; Peptidase M10, serralysin-like; SMART: peptidase, metallopeptidase. (606 aa)    
Predicted Functional Partners:
Swit_4006
TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD family protein.
 
  
 0.774
Swit_4007
TIGRFAM: type I secretion system ATPase; PFAM: ABC transporter related; SMART: AAA ATPase.
 
 
 0.730
Swit_4552
PFAM: glycoside hydrolase, family 16; Hemolysin-type calcium-binding region.
 
  
0.673
Swit_0628
PFAM: type II secretion system protein E.
  
  
 0.581
Swit_0626
PFAM: Activator of Hsp90 ATPase 1 family protein.
  
    0.569
Swit_0625
Transcriptional regulator, ArsR family; PFAM: regulatory protein, ArsR; Helix-turn-helix, type 11 domain protein.
     
 0.540
Swit_1459
Flagellar motor switch protein FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.
   
 
 0.532
Swit_1492
Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Belongs to the anti-sigma-factor antagonist family.
 
    0.483
Swit_1237
PFAM: Sulfate transporter/antisigma-factor antagonist STAS.
 
    0.454
Swit_1283
Flagellin domain protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
  
 
 0.436
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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