Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (413 aa)    
Predicted Functional Partners:
nbaC
3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
 
  
  0.927
Swit_0269
PFAM: Catalase domain protein.
   
 
 0.910
Swit_3730
PFAM: Catalase domain protein; Belongs to the catalase family.
   
 
 0.910
Swit_3414
PFAM: cyclase family protein.
  
  
 0.760
Swit_2102
PFAM: cyclase family protein.
 
  
 0.719
Swit_1881
PFAM: cyclase family protein.
  
  
 0.681
Swit_0680
PFAM: TonB-dependent receptor; TonB-dependent receptor, plug.
       0.559
Swit_0682
PFAM: regulatory protein, AsnC/Lrp family.
     
 0.521
Swit_0683
PFAM: amino acid permease-associated region.
  
    0.510
Swit_0681
PFAM: amidohydrolase; Amidohydrolase 3.
       0.494
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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