Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_0718TIGRFAM: NADPH-dependent F420 reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein. (223 aa)    
Predicted Functional Partners:
Swit_0717
FO synthase subunit 1 / FO synthase subunit 2; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB.
 
   
 0.946
Swit_0414
LPPG:FO 2-phospho-L-lactate transferase; TIGRFAM: LPPG domain containing protein; PFAM: protein of unknown function UPF0052 and CofD.
 
   
 0.810
Swit_0415
Coenzyme F420-0 gamma-glutamyl ligase; TIGRFAM: F420-dependent oxidoreductase, putative; PFAM: protein of unknown function DUF129.
 
   
 0.810
Swit_0413
Conserved hypothetical protein.
 
   
 0.753
Swit_0724
Methylenetetrahydromethanopterin reductase; PFAM: luciferase family protein.
 
  
 0.705
Swit_2098
PFAM: luciferase family protein.
 
  
 0.544
Swit_1615
Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductase-like protein.
 
  
 0.520
Swit_0716
Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein, AraC type.
       0.458
Swit_1762
PFAM: oxidoreductase domain protein.
  
  
 0.424
Swit_0704
PFAM: luciferase family protein.
 
  
 0.410
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
Server load: low (12%) [HD]