Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_0786PFAM: binding-protein-dependent transport systems inner membrane component; Substrate-binding region of ABC-type glycine betaine transport system. (517 aa)    
Predicted Functional Partners:
Swit_0787
PFAM: ABC transporter related; SMART: AAA ATPase.
 
 0.999
Swit_0784
Conserved hypothetical protein.
 
     0.759
Swit_0785
PFAM: protein of unknown function DUF323.
 
     0.718
Swit_4096
PFAM: Hemerythrin HHE cation binding domain protein.
 
  
 0.689
Swit_0443
Hypothetical protein.
  
  
 0.648
Swit_0788
Beta-lactamase; PFAM: penicillin-binding protein, transpeptidase; beta-lactamase.
 
   
 0.645
Swit_3608
HAD-superfamily hydrolase, subfamily IIB; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
   
  
 0.562
prfC
Bacterial peptide chain release factor 3 (bRF-3); Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
     
 0.530
Swit_4054
Transcriptional regulator, MarR family; PFAM: regulatory protein, MarR.
 
  
 0.528
Swit_1477
Putative adenylate/guanylate cyclase; TIGRFAM: PAS sensor protein; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; GAF domain protein; histidine kinase, HAMP region domain protein; PAS fold-4 domain protein; PAS fold domain protein.
  
  
 0.522
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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