Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_0787PFAM: ABC transporter related; SMART: AAA ATPase. (281 aa)    
Predicted Functional Partners:
Swit_0786
PFAM: binding-protein-dependent transport systems inner membrane component; Substrate-binding region of ABC-type glycine betaine transport system.
 
 0.999
Swit_2149
PFAM: protein of unknown function DUF214.
    
 0.811
Swit_4007
TIGRFAM: type I secretion system ATPase; PFAM: ABC transporter related; SMART: AAA ATPase.
 
    
0.796
Swit_3707
PFAM: ABC-2 type transporter.
    
 0.773
cysS
TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase, class Ia-like; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
     0.608
Swit_3708
PFAM: ABC-2 type transporter.
    
 0.594
rpsK
SSU ribosomal protein S11P; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
  
     0.588
Swit_0785
PFAM: protein of unknown function DUF323.
       0.581
Swit_0784
Conserved hypothetical protein.
       0.574
Swit_0788
Beta-lactamase; PFAM: penicillin-binding protein, transpeptidase; beta-lactamase.
       0.567
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
Server load: low (20%) [HD]