Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_0819Gentisate 1,2-dioxygenase; PFAM: Cupin 2, conserved barrel domain protein. (376 aa)    
Predicted Functional Partners:
Swit_3059
TIGRFAM: gentisate 1,2-dioxygenase; PFAM: Cupin 2, conserved barrel domain protein.
  
  
 
0.910
Swit_0820
5-carboxymethyl-2-hydroxymuconate Delta-isomerase; PFAM: fumarylacetoacetate (FAA) hydrolase.
 
   
 0.768
Swit_3086
Gentisate 1 2-dioxygenase-like protein.
  
   
 0.753
maiA
Asp/Glu racemase; Catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate.
 
     0.720
Swit_1879
PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase.
 
   
 0.690
Swit_4258
Gentisate 1 2-dioxygenase-like protein.
  
     0.663
Swit_1880
Indolepyruvate ferredoxin oxidoreductase; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding.
 
   
 0.650
Swit_4263
Gentisate 1 2-dioxygenase-like protein.
  
   
 0.585
Swit_0832
PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase.
 
     0.562
Swit_4606
Hypothetical protein.
 
     0.501
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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