STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swit_0839Pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase, E1 component. (327 aa)    
Predicted Functional Partners:
Swit_1225
Transketolase, central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.999
Swit_0840
PFAM: Transketolase, central region; Transketolase domain protein.
 0.994
Swit_1038
PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein.
 
 0.986
Swit_1039
PFAM: Transketolase, central region; Transketolase domain protein.
 0.984
Swit_2268
PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein.
 
 0.983
Swit_1367
Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.982
Swit_0347
PFAM: Transketolase, central region; Transketolase domain protein.
 0.980
Swit_2269
PFAM: Transketolase, central region; Transketolase domain protein.
 0.979
Swit_1056
Transketolase domain protein; PFAM: Transketolase, central region; Transketolase domain protein.
 0.976
Swit_0667
PFAM: Transketolase, central region; Transketolase domain protein.
 0.975
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.