Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_0839Pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase, E1 component. (327 aa)    
Predicted Functional Partners:
Swit_0840
PFAM: Transketolase, central region; Transketolase domain protein.
 0.994
Swit_1039
PFAM: Transketolase, central region; Transketolase domain protein.
 0.984
Swit_0347
PFAM: Transketolase, central region; Transketolase domain protein.
 0.980
Swit_1225
Transketolase, central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 0.979
Swit_2269
PFAM: Transketolase, central region; Transketolase domain protein.
 0.978
Swit_1056
Transketolase domain protein; PFAM: Transketolase, central region; Transketolase domain protein.
 0.976
Swit_0667
PFAM: Transketolase, central region; Transketolase domain protein.
 0.975
Swit_2144
Branched-chain alpha-keto acid dehydrogenase E1 component; PFAM: Transketolase, central region; Transketolase domain protein.
 0.963
Swit_0781
Branched-chain alpha-keto acid dehydrogenase E1 component; PFAM: Transketolase, central region; Transketolase domain protein.
 0.954
Swit_0841
PFAM: biotin/lipoyl attachment domain-containing protein.
 
 0.886
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.