Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_0853PFAM: OmpA domain protein transmembrane region-containing protein; surface antigen msp4 family protein; OmpA/MotB domain protein. (373 aa)    
Predicted Functional Partners:
bamA
Surface antigen (D15); Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
 
 
 0.925
Swit_0469
PFAM: outer membrane chaperone Skp (OmpH).
  
 
 0.902
Swit_2354
TIGRFAM: protease Do; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; Belongs to the peptidase S1C family.
 
 
 
 0.868
secA
Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.
   
 
 0.842
tolB
Tol-Pal system beta propeller repeat, TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
 
 0.768
Swit_0689
Hypothetical protein.
  
 
 0.767
Swit_1774
Amidohydrolase; PFAM: peptidase S9B, dipeptidylpeptidase IV domain protein; amidohydrolase; WD40 domain protein beta Propeller.
  
 
 0.710
Swit_1775
Amidohydrolase; PFAM: peptidase S9B, dipeptidylpeptidase IV domain protein; amidohydrolase; WD40 domain protein beta Propeller; Amidohydrolase 3.
  
 
 0.710
Swit_0410
PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SurA N-terminal domain.
 
 
 
 0.690
Swit_2346
TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: protein of unknown function DUF214.
 
 
 0.685
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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