Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_0863TIGRFAM: poly(R)-hydroxyalkanoic acid synthase, class I; PFAM: alpha/beta hydrolase fold; Poly-beta-hydroxybutyrate polymerase domain protein. (591 aa)    
Predicted Functional Partners:
Swit_0645
TIGRFAM: polyhydroxyalkanoate depolymerase, intracellular; PFAM: PHB de-polymerase domain protein.
 
  
 0.972
Swit_4599
TIGRFAM: acetoacetyl-CoA reductase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR.
 
 
 0.966
Swit_0631
Poly(3-hydroxyalkanoate) synthetase-like protein.
  
  
 
0.926
Swit_0862
TIGRFAM: phasin family protein.
 
  
 0.880
Swit_0630
TIGRFAM: polyhydroxyalkanoate synthesis repressor PhaR; PFAM: PHB accumulation regulatory domain protein; PHA accumulation regulator DNA-binding protein.
 
   
 0.795
Swit_0864
PFAM: aminotransferase, class I and II.
  
    0.747
clpS
ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.
       0.642
Swit_3431
PFAM: Patatin.
 
   
 0.492
Swit_3432
TIGRFAM: 3-hydroxybutyrate dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; KR.
 
  
 0.452
Swit_2760
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic enzyme domain protein; malic enzyme, NAD-binding.
 
  
 0.424
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
Server load: low (8%) [HD]