Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Swit_0885Pyroglutamyl-peptidase I; Removes 5-oxoproline from various penultimate amino acid residues except L-proline. (215 aa)    
Predicted Functional Partners:
Swit_0794
PFAM: Tetratricopeptide TPR_4.
   
 
 0.819
Swit_3839
Hypothetical protein.
    
 
 0.814
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
   0.796
Swit_0886
PFAM: alpha/beta hydrolase fold.
     
 0.779
Swit_0888
PFAM: alpha/beta hydrolase fold.
     
 0.779
Swit_0887
PFAM: Amidase; Belongs to the amidase family.
       0.773
Swit_0889
PFAM: aromatic-ring-hydroxylating dioxygenase, beta subunit.
       0.773
Swit_0890
PFAM: ring hydroxylating dioxygenase, alpha subunit; Rieske [2Fe-2S] domain protein.
       0.773
Swit_2481
PFAM: protein of unknown function DUF979.
 
    0.766
Swit_2480
PFAM: protein of unknown function DUF969.
 
     0.739
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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