Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_0888PFAM: alpha/beta hydrolase fold. (282 aa)    
Predicted Functional Partners:
Swit_0886
PFAM: alpha/beta hydrolase fold.
 
     0.935
Swit_2111
PFAM: Hydratase/decarboxylase.
 
 
 0.934
Swit_3520
PFAM: Hydratase/decarboxylase.
 
 
 0.934
Swit_1639
PFAM: Hydratase/decarboxylase.
 
 
 0.933
Swit_0911
PFAM: Hydratase/decarboxylase.
 
 
 0.932
Swit_0742
2-keto-4-pentenoate hydratase-like protein.
  
 
 0.908
Swit_0887
PFAM: Amidase; Belongs to the amidase family.
    
 0.817
Swit_0889
PFAM: aromatic-ring-hydroxylating dioxygenase, beta subunit.
 
  
 0.814
Swit_0890
PFAM: ring hydroxylating dioxygenase, alpha subunit; Rieske [2Fe-2S] domain protein.
   
 
 0.799
Swit_0885
Pyroglutamyl-peptidase I; Removes 5-oxoproline from various penultimate amino acid residues except L-proline.
     
 0.779
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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