Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Swit_0924PFAM: TonB-dependent receptor; TonB-dependent receptor, plug. (795 aa)    
Predicted Functional Partners:
Swit_1821
TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug.
  
  
 0.745
Swit_0925
PFAM: short-chain dehydrogenase/reductase SDR.
  
    0.650
Swit_3032
PFAM: TonB-dependent receptor; TonB-dependent receptor, plug.
  
     0.645
Swit_1810
PFAM: TonB-dependent receptor; Secretin/TonB, short N-terminal domain; TonB-dependent receptor, plug.
 
  
 0.595
Swit_0922
anti-FecI sigma factor, FecR; PFAM: FecR protein.
 
  
 0.565
Swit_4318
PFAM: TonB-dependent receptor; TonB-dependent receptor, plug.
  
     0.556
Swit_0921
TonB-dependent receptor, plug; PFAM: TonB-dependent receptor; Secretin/TonB, short N-terminal domain; TonB-dependent receptor, plug.
 
  
0.537
Swit_3144
PFAM: TonB-dependent receptor; TonB-dependent receptor, plug.
  
     0.513
Swit_2441
TonB family protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
 
 0.494
Swit_1868
PFAM: TonB-dependent receptor; TonB-dependent receptor, plug.
  
     0.490
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
Server load: low (14%) [HD]