STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Swit_0942PFAM: Sarcosine oxidase, gamma subunit. (176 aa)    
Predicted Functional Partners:
Swit_0943
PFAM: glycine cleavage T protein (aminomethyl transferase); FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Glycine cleavage T-protein, C-terminal barrel; Belongs to the GcvT family.
 
 0.999
Swit_0944
PFAM: Sarcosine oxidase, delta subunit, heterotetrameric.
 
 0.999
Swit_0939
PFAM: FAD dependent oxidoreductase; glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein, C-terminal barrel; Belongs to the GcvT family.
 
 0.998
Swit_0945
TIGRFAM: sarcosine oxidase, beta subunit family; PFAM: FAD dependent oxidoreductase.
 
 0.997
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.923
gcvPA
Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
     
 0.905
Swit_2697
Glycine dehydrogenase (decarboxylating) beta subunit.
     
 0.905
Swit_1176
L-threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase.
    
  0.903
Swit_3823
TIGRFAM: 5-aminolevulinic acid synthase; PFAM: aminotransferase, class I and II.
     
  0.900
purU
Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
  
  
 0.760
Your Current Organism:
Sphingomonas wittichii
NCBI taxonomy Id: 392499
Other names: S. wittichii RW1, Sphingomonas sp. RW1, Sphingomonas wittichii DSM 6014, Sphingomonas wittichii RW1, Sphingomonas wittichii str. RW1, Sphingomonas wittichii strain RW1
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